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Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography

机译：隔行光谱编码共焦扫描激光检眼镜和光谱域光学相干断层扫描

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Scanning laser ophthalmoscopy (SLO) and spectral domain optical coherence tomography (SDOCT) have become essential clinical diagnostic tools in ophthalmology by allowing for video-rate noninvasive en face and depth-resolved visualization of retinal structure. Current generation multimodal imaging systems that combine both SLO and OCT as a means of image tracking remain complex in their hardware implementations. Here, we combine a spectrally encoded confocal scanning laser ophthalmoscope (SECSLO) with an ophthalmic SDOCT system. This novel implementation of an interlaced SECSLO-SDOCT system allows for video-rate SLO fundus images to be acquired alternately with high-resolution SDOCT B-scans as a means of image aiming, guidance, and registration as well as motion tracking. The system shares the illumination source, detection system, and scanning optics between both SLO and OCT as a method of providing a simple multimodal ophthalmic imaging system that can readily be implemented as a table-top or hand-held device.
机译：扫描激光检眼镜（SLO）和光谱域光学相干断层扫描（SDOCT）通过允许视频速率的非侵入式面部和深度分辨的视网膜结构可视化，已成为眼科学中必不可少的临床诊断工具。结合了SLO和OCT作为图像跟踪手段的现代多模态成像系统在其硬件实现中仍然很复杂。在这里，我们结合了光谱编码共焦扫描激光检眼镜（SECSLO）和眼科SDOCT系统。隔行SECSLO-SDOCT系统的这种新颖实现方式允许通过高分辨率SDOCT B扫描交替获取视频速率的SLO眼底图像，以此作为图像瞄准，引导和配准以及运动跟踪的手段。该系统在SLO和OCT之间共享照明源，检测系统和扫描光学器件，作为一种提供简单的多模态眼科成像系统的方法，该系统可以很容易地实现为台式或手持式设备。

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